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【摘要】目的:比较丙戊酸钠与左乙拉西坦治疗儿童癫痫的疗效。方法:将60例癫痫患儿完全随机分为丙戊酸钠组30例,左乙拉西坦组30例。丙戊酸钠组应用丙戊酸钠治疗;左乙拉西坦组应用左乙拉西坦治疗,观察治疗效果。结果:丙戊酸钠组30例癫痫患儿治疗后无效4例、有效20例、完全控制5例、加重1例、总有效率25例(83.4%)。左乙拉西坦组30例癫痫患儿治疗后无效3例、有效18例、完全控制6例、加重3例、总有效率24例(80%)。两组总有效率的比较差异无统计学意义,即总有效率差异吴显著性。结论:丙戊酸钠和左乙拉西坦均是相对有效的小儿抗癫痫治疗药物。
【关键词】丙戊酸钠;左乙拉西坦;癫痫;儿童
【中图分类号】R729【文献标识码】A【文章编号】1007-8517(2010)12-009-2
【Abstract】Objective:To compare the sodium valproate and levetiracetam treatment of children with epilepsy. Methods:60 patients were randomly divided into sodium valproate in epileptic children complete 30 patients in the levetiracetam group of 30 patients. Application of sodium valproate sodium valproate group Treatment;Levetiracetam Levetiracetam treatment group were observed therapeutic effect. Results:The valproate group of 30 children with epilepsy treated 4 cases,effective in 20 cases,5 cases of complete control and increased in 1 case,the total effective rate of 25 cases(83.4%). Levetiracetam in children with epilepsy,30 patients after treatment and 3 cases,effective in 18 cases,complete control in 6 patients,increased in 3 cases,total effective rate of 24 cases(80%).The total effective rate of the difference was not statistically significant,difference between the total effective Wu significant. Conclusion:Sodium valproate and levetiracetam are relatively effective antiepileptic therapy in children.
【Key words】sodium valproate;Levetiracetam;epilepsy;children
