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[摘要] 目的 研究小气道功能在支气管哮喘和慢性阻塞性肺病中的临床价值。方法 通过观察两组患者舒张实验前后第一秒呼气流量(FEV1)、呼气中段流量(FEF25%~75%)的变化。结果 哮喘组经支气管舒张实验FEV1和FEF25%~75%差异有统计学意义,而FEF25%~75%在哮喘组的改善更显著。结论 小气道功能可作为区分支气管哮喘和慢性阻塞性肺病的参考指标。
[关键词] 小气道功能;支气管哮喘;慢性阻塞性肺病
[中图分类号] R562.2[文献标识码] A [文章编号] 1673-9701(2010)04-70-02
The Value of Small Airway Inflammation in Asthma and Chronic Obstructive Pulmonary Disease
WANG DejunZHAO GangWANG Chunna
Department of Respiratory Medicine,the Frist Affiliated Hospital of Baotou Medical College,Baotou 014010,China
[Abstract] Objective To study the clinical value of the small airway function in bronchial asthma and chronic obstructive pulmonary disease. Methods Before and after the bronchial dilation testing FEV1(forced expiratory volume in one second),FEF25%~75% (maximal midexpiratory flow) changes were observed in two groups of patients. Results The asthma groups of patients with FEV1 after bronchial dilation testing,and FEF25%~75% difference was statistically significant(P0.05),而1组用药后FEV1和FEF25%~ 75%与用药前比较经t检验有统计学意义(P0.05);1组改善率经t检验比较有统计学意义(P0.05)。详见表1、2。
4.2两组患者分布情况
两组FEF25%~75%改善量与改善率经χ2检验有统计学意义(P
