【www.zhangdahai.com--考察材料】
1.新疆乌鲁木齐市友谊医院骨科,新疆乌鲁木齐830001;2.新疆医科大学第五附属医院肿瘤科,新疆乌鲁木齐830011� 【摘要】目的:探讨溶骨性骨代谢生化指标尿I型胶原交联氨基末端肽、血Ⅰ型胶原交联羧基末端肽定量检测诊断前列腺癌骨转移的诊断价值。方法:用酶联免疫吸附试验(ELISA)方法测定77例前列腺癌患者尿NTx和血ICTP水平。结果:骨转移组患者尿NTx和血ICTP均明显高于无骨转移组以及正常参考值范围(P均
参考文献�
[1]Kuwahara M,Tochigi4T,Kawamura S,et al.Mass screening for prostate cancer:a comparative study in Natori,Japan and changchun,china[J].Urology,2003,61(1):137.�
[2]Kiuchi K,Ishikawa T,Hamaguchi Y,et al.Cross-linked collagen C-and N-telopeptides for an early diagnosis of bone metastasis from breast cancer.Oncol Rep,2002,9(3):595-598.�
[3]Izumi M,Nakanishi Y,Takayama K,et al.Diagnostic value of bone-turnover metabolites in the diagnosis of bone metastases in patients with lung carcinoma.Cancer,2001 Apr 15,91(8):1487-1493.�
[4]Birtle AJ,Freeman A,Masters JR,et al.Clinical features of patients who present with mestastatic prostate carcinoma and serum prostate specific antigen (PSA) lever