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【摘要】 目的 观察依那普利联合氢氯噻嗪治疗高血压的疗效。方法 将96例患者随机分为两组各48例,其中对照组只用依那普利进行治疗,观察组同时加用氢氯噻嗪,对两组疗效及治疗前后血压行比较。结果 观察组在疗效明显优于对照组。结论 依那普利联合氢氯噻嗪治疗高血压效果理想,不良反应少,适于临床应用。
【关键词】 依那普利;氢氯噻嗪;高血压
Clinical Efficacy of Enalapril combined with Hydrochlorothiazide on treatment of Hypertension
ZHANG Hong-li. Lingang Hospital of Taigang Group, Shanxi 041000, China
【Abstract】 Objective To observe the effect of enalapril combined hydrochlorothiazide on treating hypertension.Methods 96 patients were randomly divided into two groups,each with 48 cases. The control group were treated with enalapril only, while the observation group was added hydrochlorothiazide.Efficacy anf blood pressure before and after treatment of the two groups were compared.Results Efficacy of the observation group was significantly superior to that of the control group.Conclusion Enalapril combining with hydrochlorothiazide for high blood pressure has satisfactory results,less adverse reactions and is suitable for clinical application.
【Key words】 Enalapril; Hydrochlorothiazide; Hypertension
作者单位:041000山西省太钢集团临钢医院
高血压是最常见的心血管疾病,不仅患病率高,且常伴有脂肪和糖代谢紊乱及心、脑、肾和视网膜等器官损伤。积极降压治疗可减少心血管事件,有效降低发病率和死亡率[1]。山西省太钢集团临钢医院采取依那普利联合小剂量氢氯噻嗪治疗高血压,疗效满意,现报告如下。
1 资料与方法
1.1 一般资料 研究对象为本院2008年1月至2009年12月收治确诊的高血压患者96例,其中男57例,女39例,年龄29～68岁。随机分为观察组和对照组,各48例,两组间性别、年龄、基础血压等均无统计学意义(P20 mm Hg;无效:未达到上述标准。
1.4 统计学处理 采用SPSS 12.0统计软件分析,计量资料以均数±标准差(x±s)表示,采用t检验;计数资料采用χ2检验。以P
