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【摘要】 目的观察马来酸桂哌齐特注射液(克林澳)联合比索洛尔对老年阵发性室上性心动过速的临床疗效。方法 对40例符合诊断的老年阵发性室上性心动过速患者,给予马来酸桂哌齐特注射液+比索洛尔治疗14 d,观察疗效。结果 显效22例,有效15例,无效3例,总有效率92.5%,无明显不良反应。结论 马来酸桂哌齐特注射液联合比索洛尔能有效终止阵发性室上性心动过速,无明显不良反应。
【关键词】 马来酸桂哌齐特注射液;比索洛尔;阵发性室上性心动过速
Cinepazide Maleate injection combine with Bisoprolol in treatment of paroxysmal supraventricular tachycardia in elderly patient
LIU Chun-jiang,ZHANG Jiang-yu.
Department of Internal Mdeicine,
Yangcheng Hospital,the Affiliated Hospital of Guangzhou Medical College,510140,China
【Abstract】 Objective To discuss the effect of Cinepazide Maleate injection combine with Bisoprolol in treatment of paroxysmal supraventricular tachycardia in elderly patient. Methods 40 elderly patients, which were according with diagnostic standards of paroxysmal supraventricular tachycardia were treated with Cinepazide Maleate injection and Bisoprolol,evaluate the efficacy after 14 days for a course of treatment,observation curatire effect.Results 22 with significant effect , 15 with effective results and 5 with uneffect. The effective ratio was 92.5% without sid side effect. Conclusion In treatment of paroxysmal supraventricular tachycardia in elderly patients, using Cinepazide maleate injection with Bisoprolol can improve the curative effect of turn ination and no any side effect.
【Key words】 Cinepazide maleate injection;Bisoprolol;paroxysmal supraventricular tachycardia
作者单位:510140广州医学院羊城医院内科(刘春江);
广州医学院附属广东省妇儿医院病理科(张江宇)
室上性心动过速(PSVT )是常见的心律失常之一,心率多在150～250次/min,以突发、突止为特点,它可出现于无器质性心脏病或有器质性心脏病患者。发作时可表现胸闷、头晕、心悸,血压下降,少数伴有黑蒙、晕厥、心绞痛、心力衰竭、休克症状。发作持续时间过长,可引起循环功能障碍,原有器质性心脏病加重而危及生命。但常用的终止发作药物如维拉帕米、盐酸普罗帕酮(心律平)及ATP等,对老年患者尤其是合并心功能不全、严重阻塞性肺疾病者易产生严重副作用[1]。本实验通过观察马来酸桂哌齐特注射液(克林澳)联合比索洛尔对老年患者阵发性室上性心动过速的临床疗效,探讨有效控制老年患者阵发性室上性心动过速发作的方法。
1 资料与方法
1.1 病例选择 选取40例符合诊断[2]的阵发性室上性心动过速患者,其中男26例,女14例,年龄65～87岁,平均(76±11)岁,病史3 d～30年,发作持续时间0.5～42 h;其中冠心病7例,高血压10例,糖尿病6例,慢性肺原性心脏病5例,甲状腺功能亢进2例,无器质性心脏病10例;属复发病例33例,首发病例7例。排除以下情况:发作时伴有明显血流动力学障碍( SBP
