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摘 要目的：旨在探讨氯胺酮在治疗颅脑损伤方面可能的作用机理和应用前景，为临床上治疗颅脑损伤提供用药基础。方法：取大脑受伤部位，制作10%组织匀浆液检测SOD和MDA。结果使用氯胺酮治疗后能使SOD活性下降和MDA值的升高幅度有所降低，氯胺酮治疗组与同时间段的模型对比较，差异显著（P
4结论
氯胺酮能减少脑损伤后自由基产生，抑制炎症反应，减轻继发性损伤。
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